The Clinically Smart Anti-Aging Protocol
The Clinically Smart Anti-Aging Protocol

Bringing Health to Beauty™

The Clinically Smart Anti-Aging Protocol

 Clinically smart aging starts with consistency—not complexity.

Most anti-aging routines overwhelm your skin with too many actives, too quickly—leading to irritation, inflammation, and ultimately worse results.

The Clinically Smart Anti-Aging Protocol is different.

It follows a dermatologist-backed principle:
Protect during the day. Renew at night. Support your barrier always.

No unnecessary steps. No competing actives. Just what your skin actually needs to age well.

What’s inside: 

  • C Cleanser
    A gentle, barrier-safe cleanser that removes impurities without disrupting skin function.
  • Vc Vitamin C Serum
    Provides antioxidant protection, supports collagen, and helps maintain even tone.
  • M2 Rich Moisturizer
    Hydrates and reinforces the skin barrier to maintain resilience.
  • R Retinoid 
    Supports early cellular turnover and long-term skin renewal.
  • B Balm 
    Seal in moisture, reduce transepidermal water loss, and enhance tolerance to actives.

Who This Is For

  • Those looking for a results-driven anti-aging routine
  • Anyone concerned with fine lines, wrinkles, and loss of elasticity
  • Skin experiencing early to moderate signs of aging
  • Those who want to improve tone, texture, and overall radiance
  • Anyone ready to incorporate clinically proven actives like vitamin C and retinoids
  • Those who want visible results without compromising skin health
  • People seeking a simple, dermatologist-designed routine that covers both prevention and correction
  • Anyone who values long-term skin health and consistency over quick fixes
Regular price $371.00
Sale price $412.00

Your complete, personalized skin care routine:

MORNING

Step 1: C Cleanser
Gently cleanse to remove overnight oil and impurities while maintaining your skin barrier. No need to double cleanse—C Cleanser effectively removes makeup, sunscreen, and impurities in one step without stripping your skin.

Step 2: Vc Vitamin C Serum
Apply to dry skin to help defend against oxidative stress, support collagen health, and improve overall brightness and tone.

Step 3: Sunscreen (SPF, essential but not included)
Finish with SPF to protect against UV damage—the leading cause of premature aging. This step is non-negotiable for maintaining results.

Step 4: M2 Rich Moisturizer
Replenish hydration and support barrier repair while your skin undergoes overnight renewal.

EVENING

Step 1: C Cleanser
Gently cleanse to remove overnight oil and impurities while maintaining your skin barrier. No need to double cleanse—C Cleanser effectively removes makeup, sunscreen, and impurities in one step without stripping your skin.

Step 2: R Retinoid Serum
Apply daily to dry skin on the face, neck and chest to support cellular turnover, improve texture, and reduce the appearance of fine lines over time.

Step 3: B Balm

Replenish hydration and support overnight barrier repair. This step helps minimize irritation and maximize the benefits of your retinoid.

The Clinically Smart Anti-Aging Protocol insights:

Aging well isn’t about doing more—it’s about doing what works, consistently.

Most anti-aging routines overload the skin with too many actives, leading to irritation, inconsistency, and ultimately diminished results. The Clinically Smart Anti-Aging Routine takes a different approach: protect during the day, renew at night, and support the barrier at every step.

By combining clinically proven ingredients with a barrier-first philosophy, this system prioritizes long-term skin health over short-term intensity. Because the best results don’t come from pushing your skin—they come from giving it exactly what it needs, and nothing it doesn’t.

Aging well isn’t about one hero ingredient—it’s about how your routine works together. The Defend + Renew Protocol is designed as a complete system: cleanse without disrupting the barrier, defend against daily oxidative stress, stimulate renewal at night, and continuously restore barrier function. Each step is formulated to enhance the next, so your skin can tolerate actives, stay resilient, and deliver consistent results over time.

C Cleanser uses ultra-gentle, hypoallergenic surfactants to cleanse without irritation, paired with niacinamide to support barrier repair. By day, our Vitamin C Serum uses tetrahexyldecyl ascorbate—a stable, penetrating form of vitamin C—alongside ergothioneine, niacinamide, and squalane to protect against free radicals, support collagen, and brighten tone without common irritants. At night, our Retinoid Serum features hydroxypinacolone retinoate (HPR), a next-generation retinoid shown to stimulate collagen and cellular turnover with significantly less irritation, supported by squalane to maintain barrier integrity.

M2 Rich Moisturizer completes the system by restoring the essential lipids—ceramides, cholesterol, and fatty acids—needed for a healthy barrier, while niacinamide and acetyl glucosamine work synergistically to hydrate, repair, and even skin tone. By avoiding known irritants and prioritizing low-allergen formulations, this routine delivers both the biological and visible benefits of anti-aging—without compromising skin health.

C Cleanser

Aloe Barbadensis Leaf Juice, Water (Aqua) (Eau), Sodium Cocoamphodiacetate, Sodium Cocoyl Glutamate, Glycerin, C14-16 Olefin Sulfonate, Hydroxypropyl Methylcellulose, Lactobacillus Ferment, Niacinamide (1%), Disodium Acetyl Glucosamine Phosphate, Gluconolactone

Vc Vitamin C Serum

Aloe barbadensis leaf juice, Tetrahexyldecyl ascorbate (15%), Polyglyceryl-6 stearate, 1,2-hexanediol, Water (aqua), Polyglyceryl-6 polyricinoleate, Glycerin, Sodium stearoyl glutamate, Hydroxyacetophenone, Cetearyl alcohol, Polyglyceryl-6 behenate, Squalane, Carbomer, Xanthan gum, Ergothioneine, Niacinamide (0.1%), Sodium phytate, Sodium hydroxide

R Retinoid Serum

Water, Aloe Barbadensis Leaf Juice, Squalane, Caprylic/Capric Triglyceride, Glycerin, Polyglyceryl-3 Methylglucose Distearate, 1,2, Hexanediol, Dimethyl Isosorbide, Cetearyl Alcohol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Acetyl Glucosamine, Xanthum Gum, Carbomer, Hydroxypinacolone Retinoate (2%), Sodium Phytate, Ceramide NP, Ceramide AP, Glutathione, Sodium Hydroxide, Ubiquinone

M2 Rich Moisturizer

Water (aqua), Vitis vinifera (grape) seed oil, Glycerin, Heptyl undecylenate, Glyceryl stearate, Cetearyl alcohol, Caprylic/capric triglyceride, Carbomer, Phytosterols, 1,2-hexanediol, Caprylyl glycol, Sodium stearoyl lactylate, Sodium stearoyl glutamate, Gluconolactone, Sodium hydroxide, Phospholipids, Ceramide np, Trehalose, Ceramide ap, Disodium acetyl glucosamine phosphate, Tricholoma matsutake mycelium ferment extract, Tropolone, Hydrolyzed sodium hyaluronate, Ergothioneine

B Balm

Water/Aqua/Eau, C9-C12 Alkane, Butyrospermum Parkii (Shea) Butter, Diheptyl Succinate, Glyceryl Stearate SE, Cetyl Alcohol, Cetearyl Alcohol, 1,2-Hexanediol, Glyceryl Behenate, Glycerin, Coco Caprylate/Caprate, Squalane, Cetyl Stearate, Triheptanoin, Hydroxyacetophenone, Dilinoleic Acid/Butanediol Copolymer, Arginine, Carbomer, Sodium Stearoyl Glutamate, Avena Sativa (Oat) Kernel Extract, Phospholipids, Capryloyl Glycerin/Sebacic Acid Copolymer, Ricinus Communis (Castor) Seed Oil, Zinc Gluconate, Glutathione, Sodium Phytate, Sodium Hydroxide, Ceramide NP, Ceramide AP, Castor Oil/IPDI Copolymer, 7-Dehydrocholesterol

Our products are made in the US with ingredients that are vegan, cruelty-free, and responsibly sourced and packaged in recyclable glass and paper. 

  1. Zasada M, Budzisz E. Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments. Postepy Dermatol Alergol. 2019 Aug;36(4):392-397. doi: 10.5114/ada.2019.87443. Epub 2019 Aug 30. PMID: 31616211; PMCID: PMC6791161
  2. Ruth, N., and T. Mammone. "Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models." Journal of Investigative Dermatology 138.5 (2018): S223
  3. Temova Rakuša Ž, Škufca P, Kristl A, Roškar R. Retinoid stability and degradation kinetics in commercial cosmetic products. J Cosmet Dermatol. 2021 Jul;20(7):2 350-2358. doi: 10.1111/jocd.13852. Epub 2020 Dec 2. PMID: 33206444.

Our products are packaged in recyclable glass and paper.

Find out what makes Vetted, Vetted®.

Hypoallergenic skincare engineered for lasting skin health. Our ingredients are science-backed, ethically sourced and truly hypoallergenic.

Our formulations were designed by our dermatologists. Every ingredient is carefully selected using the most up-to-date scientific evidence on efficacy, irritant, and allergenic potential.

We exclude ingredients that are known endocrine disruptors or for which there is credible evidence of concerning health or environmental toxic effects.

Our products don't have any fragrances or fragrance cross-reactors. 

We don't include any ingredients that are common (or uncommon, for that matter) causes of allergic contact dermatitis.

All of our products undergo repeat insult patch testing. There are no reports of irritant or allergic reactions with testing of our formulations. 

Phthalates are known endocrine disruptors. We don't include any phthalates in our formulations and we package our products in glass (which does not leach phthalates). 

We do not test any of our formulations on animals. 

All products are packaged in recyclable glass bottles. 

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